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2006 Mercedes-Benz E350 Fuel/propulsion System Problems

NHTSA component category: FUEL/PROPULSION SYSTEM · data through 07/12/2026

144Fuel/propulsion System complaints
36.2%Of all 398 complaints
#1Most-reported category

Source: U.S. NHTSA complaint data. Complaints are unverified reports from vehicle owners — a complaint is not a confirmed defect.

How fuel/propulsion system ranks on this vehicle

FUEL/PROPULSION SYSTEM144 · 36.2%
ENGINE50 · 12.6%
SERVICE BRAKES46 · 11.6%
POWER TRAIN29 · 7.3%

Share of the 398 complaints citing each category; one complaint can cite several. Full breakdown on the 2006 Mercedes-Benz E350 overview page.

What owners report

“THE CONTACT OWNS A 2006 MERCEDES E-350. THE CONTACT STATED THAT AFTER THE VEHICLE WAS PARKED OVERNIGHT, THE CONTACT LATER NOTICED GASOLINE FUMES INSIDE THE…”NHTSA complaint 10511251 — filed 05/09/2013
“I AM EXPERIENCING HIGHLY INTOXICATING FUMES COMING FROM THE VEHICLE GAS TANK. I CAN NO LONGER PARK VEHICLE INSIDE MY GARAGE FOR FEAR OF AN…”NHTSA complaint 10509707 — filed 04/26/2013
“FOLLOWING FILL-UP AND ONLY WHEN TANK IS FUEL, STRONG ODOR OF FUEL IN GARAGE. TALKED TO MECHANIC THAT INSPECTED VEHICLE. FOUND RESEARCH ONLINE DESCRIBING SIMILAR…”NHTSA complaint 10509114 — filed 04/22/2013

Excerpts are shortened and scrubbed of personal details; they are individual, unverified reports.

Fuel/propulsion System complaints by year filed

16201230201335201422201592016122017420183201942020420214202212023

Frequently asked questions

Does the 2006 Mercedes-Benz E350 have fuel/propulsion system problems?

Fuel/propulsion System is the most-reported problem area on the 2006 Mercedes-Benz E350: 144 of 398 complaints on file (36.2%). Complaints are unverified owner reports, not confirmed defects.

How many complaints does the 2006 Mercedes-Benz E350 have in total?

398 complaints were on file with NHTSA as of 07/12/2026. Across all categories, 14 involved a crash, 9 involved a fire, 18 reported injuries, and 1 reported deaths.

What does NHTSA's fuel/propulsion system category include?

NHTSA assigns each complaint to standard component categories; this page reports the FUEL/PROPULSION SYSTEM category exactly as NHTSA defines and records it.

About this data — Complaint figures on this page are consumer reports submitted to the National Highway Traffic Safety Administration (NHTSA), a U.S. government agency. NHTSA does not verify individual complaints; a complaint is not proof that a defect exists, and counts reflect what owners chose to report, not confirmed failure rates. Recall information comes from official NHTSA safety recall campaigns; recall repairs are free at authorized dealers. Always check your specific vehicle by VIN at nhtsa.gov/recalls. CarModelProblems.com is an independent site and is not affiliated with NHTSA or any vehicle manufacturer. Data through 07/12/2026.